North East and North Cumbria
ICS Formulary
 
back
9 Nutrition and blood
09-01-03 Drugs used in hypoplastic, haemolytic, and renal anaemias

Crovalimab Piasky®
Formulary
  • 340 mg solution for injection/infusion
  • Approved as an option for treating paroxysmal nocturnal haemoglobinuria in people 12 years and over who weigh 40 kg or more in line with NICE
Link  NICE TA1019: Crovalimab for treating paroxysmal nocturnal haemoglobinuria in people 12 years and over

Red View adult BNF  View SPC online  View childrens BNF  HCD
Danicopan Voydeya®
Formulary
  • 50mg, 100mg tablets
  • Approved as an add-on to ravulizumab or eculizumab as an option for treating paroxysmal nocturnal haemoglobinuria (PNH) in adults who have residual haemolytic anaemia in line with NICe

Paroxysmal nocturnal haemoglobinuria treatment is only commissioned from:

  • King’s College Hospital NHS Foundation Trust, London - London and South East
  • Leeds Teaching Hospitals NHS Trust - Rest of United Kingdom
Link  NICE TA1010: Danicopan with ravulizumab or eculizumab for treating paroxysmal nocturnal haemoglobinuria

Red View adult BNF  View SPC online  View childrens BNF  HCD
Eculizumab
Formulary
  • 300mg/30ml solution for infusion
  • Approved treating atypical haemolytic uraemic syndrome in adults and children in line with NICE

Paroxysmal nocturnal haemoglobinuria treatment is only commissioned from:

  • King’s College Hospital NHS Foundation Trust, London - London and South East
  • Leeds Teaching Hospitals NHS Trust - Rest of United Kingdom
Link   NICE TA647: Eculizumab for treating relapsing neuromyelitis optica (terminated appraisal)
Link  Clinical Commissioning Policy: Eculizumab in the treatment of recurrence of C3 glomerulopathy postkidney transplant (all ages) Reference: NHS England: 16054/P
Link  NICE HST 1 - Eculizumab for treating atypical haemolytic uraemic syndrome
Link  NICE TA636: Eculizumab for treating refractory myasthenia gravis (terminated appraisal)

Red View adult BNF  View SPC online  View childrens BNF  HCD
Iptacopan Fabhalta®
Formulary
  • 200mg hard capsules
  • Approved for treating paroxysmal nocturnal haemoglobinuria (PNH) in adults with haemolytic anaemia in line with NICE

Paroxysmal nocturnal haemoglobinuria treatment is only commissioned from:

  • King’s College Hospital NHS Foundation Trust, London - London and South East
  • Leeds Teaching Hospitals NHS Trust - Rest of United Kingdom
Link  NICE TA1000 : Iptacopan for treating paroxysmal nocturnal haemoglobinuria

Red View adult BNF  View SPC online  HCD
Pegcetacoplan Aspaveli®
Formulary
  • 1080mg/20 solution for infusion
  • Approved for the treatment paroxysmal nocturnal haemoglobinuria in adults who have anaemia after at least 3 months of treatment with a C5 inhibitor in line with NICE and NHSE Commissioning Policy.
  • Paroxysmal nocturnal haemoglobinuria treatment is only commissioned from:
    • King’s College Hospital NHS Foundation Trust, London - London and South East
    • Leeds Teaching Hospitals NHS Trust - Rest of United Kingdom

 

Link  NICE TA778: Pegcetacoplan for treating paroxysmal nocturnal haemoglobinuria

Red View adult BNF  View SPC online  View childrens BNF
Ravulizumab Ultomiris®
Formulary
  • 300mg/30ml & 1,100mg/11ml concentrate for solution for infusion
  • Approved for the treatment of paroxysmal nocturnal haemoglobinuria in adults in line with NICE
  • Approved for the treatment of atypical haemolytic uraemic syndrome in line with NICE
  • Paroxysmal nocturnal haemoglobinuria treatment is only commissioned from 
    • King’s College Hospital NHS Foundation Trust, London - London and South East
    • Leeds Teaching Hospitals NHS Trust - Rest of United Kingdom
Link  NICE TA698: Ravulizumab for treating paroxysmal nocturnal haemoglobinuria
Link  NICE TA710: Ravulizumab for treating atypical haemolytic uraemic syndrome

Red View adult BNF  View SPC online  View childrens BNF
Roxadustat Evrenzo®
Formulary
  • 20mg, 50mg, 70mg, 100mg and 150mg tablets
  • Approved for treating symptomatic anaemia associated with chronic kidney disease in adults in line with NICE
Link  NICE TA807: Roxadustat for treating symptomatic anaemia in chronic kidney disease

Red View adult BNF  View SPC online  View childrens BNF
Vadadustat Vafseo®
Formulary
  • 150mg, 300 mg film coated tablets
  • Approved as an option for treating symptomatic anaemia caused by chronic kidney disease in adults having maintenance dialysis in line with NICE
Link  NICE TA1035: Vadadustat for treating symptomatic anaemia in adults having dialysis for chronic kidney disease

Red View adult BNF  View SPC online  View childrens BNF