North East and North Cumbria
ICS Formulary
 
back
8 Malignant disease and immunosuppression
08-01 Drugs for cytotoxic-induced side-effects

Calcium Folinate
Formulary
  • Approved for methotrexate-induced mucositis and myelosuppression. The following formulations are approved:
    • 15mg tablets.
    • 3mg, 15mg, 30mg, and 300mg injections
    • A calcium folinate 1mg per ml mouthwash can be prepared if needed.unlicensedunlicensed

Red View adult BNF  View SPC online  View childrens BNF
Dexrazoxane  Savene®
Formulary
  • For use in line with NECN extravasation.

Red View adult BNF  View SPC online  View childrens BNF
Glucarpidase  Voraxaze®
Formulary
  • 1,000 units powder for solution for injection
  • Approved for the urgent treatment of methotrexate-induced renal
    dysfunction.
Link  NHS England: Glucarpidase for the urgent treatment of methotrexateinduced renal dysfunction

Red View adult BNF  View SPC online  View childrens BNF
Mesna
Formulary
  • Approved formulations include 1gram in 10ml injection and 400mg tablets.

Red View adult BNF  View SPC online  View childrens BNF
Sodium thiosulfate (anhydrous) Pedmarqsi®
Formulary
  • 80 mg/mL solution for infusion
  • Approved for preventing hearing loss caused by cisplatin chemotherapy in people 1 month to 17 years with localised, non-metastatic solid tumours in line with NICE
Link  NICE TA1034: Anhydrous sodium thiosulfate for preventing hearing loss caused by cisplatin chemotherapy in people 1 month to 17 years with localised solid tumours

Red View adult BNF  View SPC online  View childrens BNF