North East and North Cumbria
ICS Formulary
 
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6 Endocrine system
06-04-01-01 Hormone replacement therapy

Sequential combined HRT
Formulary
  • Oral options
    • Elleste Duet - estradiol 1mg or 2mg +/- norethisterone 1mg
    • Femoston - estradiol 1mg or 2mg +/- dydrogesterone 10mg
  • Transdermal options - patches
    • Evorel Sequi - estradiol +/- norethisterone acetate 

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Continuous combined HRT
Formulary
  • Oral options
    • Elleste Duet Conti - estradiol 2mg + norethisterone 1mg
    • Femoston Conti - estradiol 0.5mg + dydrogesterone 2.5mg; estradiol 1mg + dydrogesterone 5.0mg
    • Kliovance - estradiol 1mg + norethisterone acetate 500 micrograms
    • Kliofem - estradiol 2mg + norethisterone acetate 1mg
    • Bijuve - estradiol 1mg + progesterone 100mg
  • Transdermal options - patches
    • Evorel Conti - estradiol 50 micrograms/24 hours + norethisterone acetate 170 micrograms/24hours
    • Femseven Conti - estradiol 50 micrograms/24 hours + levonorgestrel 7 micrograms/24 hours

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Estradiol unopposed oestrogen
Formulary
  • Oral estradiol
    • Elleste® Solo - 1mg & 2mg tablets
  • Transdermal estradiol - patches - TWICE weekly
    • Estradot® - 25, 37.5, 50, 75, & 100 microgram patches
    • Evorel® - 25, 50, 75, & 100 microgram patches
  • Transdermal estradiol - patches - ONCE weekly
    • Femseven® - 25, 50, 75, & 100 microgram patches
  • Transdermal estradiol - gel - option where skin irritation occurs with patch
    • Oestrogel® 0.06% gel 
    • Sandrena® - 0.5mg or 1mg 
  • Transdermal estradiol - spray - alternative to patches and gels for patients who have issues with absorption, find patch adhesive irritating or the gel messy
    • Lenzetto® 1.53mg/spray - 1-3 sprays daily 

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Ethinylestradiol unopposed oestorgen
Formulary

2 microgram tablets, unlicensed unlicensed.


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Estradiol vaginal tablet
Formulary

10mg vaginal tablet

Take into consideration patient preference for applicator device. If patient has no preference for a specific device, prescribe generically.

NB: Vagirux has a reusable applicator and other products do not.

 


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Oestrogen, conjugated
Formulary

625microgram and 1.2mg tablets


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Tibolone
Formulary

2.5mg tablets


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