North East and North Cumbria
ICS Formulary
 
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6 Endocrine system
06-07 Other endocrine drugs

Cerliponase alfa Brineura®
Formulary
  • 150 mg solution for infusion
  • Approved as an option for treating neuronal ceroid lipofuscinosis type 2 (CLN2), also known as tripeptidyl peptidase 1 (TPP1) deficiency in line with NICE
Link  NICE HST12 : Cerliponase alfa for treating neuronal ceroid lipofuscinosis type 2

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Ketoconazole Ketoconazole HRA
Formulary
  • 200mg Tablets
  • Indicated for Cushing's Syndrome 

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Setmelanotide Imcivree®
Formulary
  • 10mg/1ml vial for injection
    • Approved for treating obesity caused by LEPR or POMC deficiency in people 6 years and over in line with NICE and any associated NHSE Commissioning Guidance
    • Approved for treating obesity and hyperphagia in Bardet-Biedl syndrome in people 6 years and over, only if they are between 6 and 17 years when treatment starts in line with NICE and any associated NHSE Commissioning Guidance
Link  NICE HST21: Setmelanotide for treating obesity caused by LEPR or POMC deficiency
Link  NICE HST31: Setmelanotide for treating obesity and hyperphagia in Bardet-Biedl syndrome

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