North East and North Cumbria
ICS Formulary
 
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4 Central nervous system
04-09-03 Drugs used in essential tremor, chorea, tics, and related disorders

Botulinum Toxin Type A Botox®
Formulary
  • Botox also approved for use in paediatric patients with severe bladder over- activity and neuropathic bladder who have not responded to other treatment.
  • Prescribe by brand name.

 

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Botulinum Toxin Type A Dysport®
Formulary

  • Prescribe by brand name.

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Botulinum Toxin Type A Vistabel®
Formulary
  • Restricted to use in private patients receiving aesthetic treatment.
  • Prescribe by brand name.

 

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Botulinum Toxin Type A injection Xeomin®
Formulary
  •  50, 100 & 200 unit powder for solution for injection
    • Approved for the treatment of chronic sialorrhoea in line with NICE
    • Similar potency to Botox®, and may be less expensive (depending on price agreements/ contracts), but not licensed for the full range of indications.
    • Prescribe by brand name.



 
Link  NICE TA605: Xeomin (botulinum neurotoxin type A) for treating chronic sialorrhoea

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Botulinum Toxin Type B NeuroBloc®
Formulary

  • Prescribe by brand name

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Riluzole
Formulary
  • 50mg tablets; 50mg orodispersible tablets (Emylif); 5mg/1ml oral suspension
  • Approved for motor neurone disease in line with NICE. 
  • Note: riluzole orodispersible film and oral suspension approved only when other preparations (including crushing tablets) are not suitable.
Link  NENC Shared Care Protocol - riluzole for patients in adult services
Link  NICE TA20: Motor neurone disease - riluzole

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Tetrabenazine
Formulary
  • For use on the advice of neurologists. 

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Memantine
Formulary
  • Approved for use as last line drug after other alternatives have been considered, in the treatment of congenital and acquired nystagmus.

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