North East and North Cumbria
ICS Formulary
 
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4 Central nervous system
04-09-03 Drugs used in essential tremor, chorea, tics, and related disorders

Botulinum Toxin Type A Botox®
Formulary
  • Botox also approved for use in paediatric patients with severe bladder over- activity and neuropathic bladder who have not responded to other treatment.
  • Prescribe by brand name.

 

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Botulinum Toxin Type A Dysport®
Formulary

  • Prescribe by brand name.

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Botulinum Toxin Type A Vistabel®
Formulary
  • Restricted to use in private patients receiving aesthetic treatment.
  • Prescribe by brand name.

 

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Botulinum Toxin Type A injection Xeomin®
Formulary
  •  50, 100 & 200 unit powder for solution for injection
    • Approved for the treatment of chronic sialorrhoea in line with NICE
    • Similar potency to Botox®, and may be less expensive (depending on price agreements/ contracts), but not licensed for the full range of indications.
    • Prescribe by brand name.



 
Link  NICE TA605: Xeomin (botulinum neurotoxin type A) for treating chronic sialorrhoea

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Botulinum Toxin Type B NeuroBloc®
Formulary

  • Prescribe by brand name

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Riluzole
Formulary
  • 50mg tablets; 50mg orodispersible tablets (Emylif); 5mg/1ml oral suspension
  • Approved for motor neurone disease in line with NICE. 
  • Note: use the most cost-effective tolerated formulation. Orodispersible tablets and oral suspension are lower cost formulations, only use plain tablets for when these other options are not suitable.  Orodispersible tablets are not always tolerated due to taste. 
Link  NENC Shared Care Protocol - riluzole for patients in adult services
Link  NICE TA20: Motor neurone disease - riluzole

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Tetrabenazine
Formulary
  • For use on the advice of neurologists. 

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Memantine
Formulary
  • Approved for use as last line drug after other alternatives have been considered, in the treatment of congenital and acquired nystagmus.

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