North East and North Cumbria
ICS Formulary
 
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4 Central nervous system
04-01-01 Hypnotics

Melatonin
Formulary
  • 2mg modified-release tablets (prescribe generically)
  • 1mg, 2mg, 3mg, 4mg, 5mg tablets (Adaflex®, crushed if necessary)
  • Restricted Item restricted use: 1mg/ml oral solution (Consilient brand)

NB: Slenyto is no longer approved. Patients should be reviewed at their next routine follow-up, see separate entry

Approved Indications

Green 

  • Insomnia (short term use – Max 13 weeks) adults 55 years and over

Green plus

  • Delayed sleep phase syndrome and other circadian rhythm disorders (including visually impaired/blind people with disturbed sleep wake cycles)
  • Patients with injurious parasomnia including REM sleep behaviour disorder (RBD) [e.g with degenerative conditions such as Parkinsonian disease or dementia]
  • Sleep conditions in patients with learning disabilities and behaviour that challenges (where sleep hygiene measures have been insufficient)
  • Neurological or behavioural disorders including:
    • Attention deficit hyperactivity disorder (ADHD)
    • Autism Spectrum Disorder (ASD)
    • Neurodevelopmental disabilities  
  • Cluster headache 
  • Prior to examinations as directed by paediatric specialists (such as a sleep encephalogram (EEG) & sedation prior to scans)

Red  

  • Critical care short term sleep disturbance [Hospital use only]

Indications not listed on the formulary are not routinely supported for prescribing e.g. sleep disturbances related to shift work, Alzheimer's disease, chronic fatigue syndrome / myalgic encephalomyelitis / encephalopathy, sleep apnoea, as an adjunct to hypnotic withdrawal and jet lag (unless an approved indication co-exists)


View adult BNF  View SPC online  View childrens BNF
Melatonin Slenyto®
Non Formulary

Not considered a cost-effective formulation. 

Patients should be reviewed at their next routine follow-up. 


Not Recomended View adult BNF  View SPC online  View childrens BNF