North East and North Cumbria
ICS Formulary
 
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2 Cardiovascular system
02-06-02 Calcium-channel blockers

Amlodipine
First Choice
  • Preferred calcium channel blocker for treating hypertension.
    • If a 10mg dose is not tolerated e.g. due to leg/ankle
      oedema, consider reducing dose before changing to an
      alternative such as lercanidipine.

Link  MHRA Drug Safety Update (Dec 2014): Simvastatin: dose limitations with concomitant amlodipine or diltiazem

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Diltiazem
First Choice
  • Preferred calcium channel blocker for angina.
  • Zemtard® is the formulary brand of choice for starting new patients on long acting diltiazem.
Link  MHRA Drug Safety Update (Dec 2014): Simvastatin: dose limitations with concomitant amlodipine or diltiazem

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Felodipine
Formulary
  • M/R tablets: 2.5mg, 5mg, 10mg 

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Nimodipine Injection
Formulary
  • 10mg in 50ml for IV infusion 

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Verapamil Injection
Formulary
  • Injection: 5mg/2ml (2.5mg/1ml) 

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Lercanidipine
Formulary
  • For use as a second line calcium channel blocker where amlodipine is not tolerated. 

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Nifedipine
Formulary
  • Once daily formualtions are preferred
  • 20mg controlled release tablets (Adalat LA), 30mg & 60mg m/r capsules (Coracten XL)
  • 5mg & 10mg capsules
  • 10mg & 20mg retard tablets
  • 20mg in 1ml (1mg/drop) nifedipine oral solution is also approved for use unlicensedunlicensed.

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Verapamil
Formulary
  • Tablets - 40mg, 80mg, 120mg
  • MR Tablets - 240mg
  • Oral Solution - 40mg/5ml

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Nimodipine
Formulary
  • 30mg tablets - treatment should be on the advice of the stroke team or a cardiologist.

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Nicardipine 1mg in 1ml injection
Formulary
  • Approved as a second line agent for the treatment of aortic dissection and pre-eclampsia.

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Verapamil 160mg tablets
Non Formulary

160mg tablets

 

For preferred preparations, see main formulary entry above


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