North East and North Cumbria
ICS Formulary
10 Musculoskeletal and joint diseases
10-02-02 Nocturnal leg cramps
Quinine sulfate
Formulary
200mg & 300mg tablets
Approved for nocturnal leg cramps in accordance with MHRA advice
Links
Guidelines for the Management of Adults with Asymptomatic Liver Blood Test Abnormalities
MHRA Drug Safety Update (Jan 2026): Improving Information Supplied with Gabapentinoids (Pregabalin/Gabapentin), Benzodiazepines and Z-Drugs
NENC Shared Care Protocol: Sativex for the treatment of spasticity in multiple sclerosis
NHS England Urgent Clinical Commissioning Policy Statement (170018/P)
NICE NG144: Cannabis-based medicinal products
NICE TA1031:Vamorolone for treating Duchenne muscular dystrophy in people 4 years and over
NICE TA1069: Efgartigimod for treating antibody-positive generalised myasthenia gravis
NICE TA588: Nusinersen for treating spinal muscular atrophy
NICE TA748: Mexiletine for treating the symptoms of myotonia in non-dystrophic myotonic disorders
NICE TA755: Risdiplam for treating spinal muscular atrophy
NTAG: Transanal irrigation (TAI) systems (Peristeen Plus®, Aquaflush®, and QuFora®) for neurogenic bowel dysfunction, chronic constipation and chronic faecal incontinence
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