North East and North Cumbria
ICS Formulary
 
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1 Gastro-intestinal system
01-05-02 Corticosteroids

Prednisolone
Formulary

The lowest cost formulation should be used when clinically appropriate.  Formulations approved include:

  • 1mg, 5mg tablets;
  • 1mg in 1ml oral solution (Prednisolone Dompé®);
  • 5mg soluble tablets - to be restricted to patients who have a genuine need e.g. swallowing difficulties. 5mg plain tablets can be dispersed in water (an off-label administration method) which may be suitable for most patients.

See separate entry for rectal formulations


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Budesonide
Formulary
  • Alternative
    • Budenofalk® (3mg capsules enclosing e/c pellets)
    • Entocort® (3mg capsules enclosing e/c m/r pellets)
    • For use on consultant gastroenterologist advice only
  • Oral Viscous Budesonide unlicensed unlicensed Red
    • For the treatment of eosinophilic oesophagitis.
    • 0.5mg or 1mg nebule is added to 13ml of syrup and this is then mixed and swallowed. 
  • Orodispersible tablet (Jorveza®) 
    • For the treatment of eosinophilic oesophagitis in adults in line with NICE Red
    • Approved for the maintenance of eosinophilic oesophagitis in line with NTAG Green plus 
  • 9mg MR tablet (Cortiment®) Red
    • For induction of remission in patients with mild to moderate active ulcerative colitis (UC) where 5-ASA treatment is not sufficient.
    • 8 week course to be provided by secondary care.
  •  4mg modified-release capsules (Kinpeygo®) Red 
    • Approved for treating primary IgA nephropathy in line with NICE
Link  NICE TA708 - Budesonide orodispersible tablet for inducing remission of eosinophilic oesophagitis
Link  NICE TA937: Targeted-release budesonide for treating primary IgA nephropathy
Link  NTAG Treatment Appraisal: Budesonide orodispersible (Jorveza®) for maintenance treatment of eosinophilic oesophagitis

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Prednisolone
Formulary

5mg suppositories only

 

See separate entry for oral prepartions


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Budesonide
Formulary
  • Green 2mg foam enema
  • Green plus 4mg suppositories (Budenofalk®), for specialist inititiation

 


View adult BNF  View SPC online  View childrens BNF