North East and North Cumbria
ICS Formulary
1 Gastro-intestinal system
01-04-02 Antimotility drugs
Loperamide
First Choice
2mg tablets and capsules
2mg orodispersible tablets:
approved for use in patients with high output stoma only when crushing tablets or opening capsules has failed. Also apporved for oral cancer patients struggling to take capsules
MHRA Drug Safety Alert Sept 2017: Loperamide (Imodium): Reports of serious cardiac adverse reactions with high doses of loperamide associated with abuse or misuse
Teduglutide
Revestive
®
Formulary
Approved for treating short bowel syndrome in people 1 year and above in line with NICE
NICE TA804: Teduglutide for treating short bowel syndrome
Codeine
Formulary
MHRA Drug Safety Update (Dec 2014): Codeine for analgesia: restricted use in children because of reports of morphine toxicity
MHRA Drug Safety Update (Dec 2014): Codeine: very rare risk of side-effects in breastfed babies
Links
Guidelines for the Management of Adults with Asymptomatic Liver Blood Test Abnormalities
MHRA Drug Safety Alert Sept 2017: Loperamide (Imodium): Reports of serious cardiac adverse reactions with high doses of loperamide associated with abuse or misuse
MHRA Drug Safety Update (Dec 2014): Codeine for analgesia: restricted use in children because of reports of morphine toxicity
MHRA Drug Safety Update (Dec 2014): Codeine: very rare risk of side-effects in breastfed babies
NICE CG84: Diarrhoea and vomiting in children under 5
NICE TA471 Eluxadoline for treating irritable bowel syndrome with diarrhoea
NICE TA804: Teduglutide for treating short bowel syndrome
NTAG: Transanal irrigation (TAI) systems (Peristeen Plus®, Aquaflush®, and QuFora®) for neurogenic bowel dysfunction, chronic constipation and chronic faecal incontinence
Key
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